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Research Awards Archive

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Research Awards since 2000 prior to 2007 are listed here in reverse date order (latest year first) sorted by the size of the grant.  The total for each year is shown at the end of that year's listings.

2007

Professor David Rampton - Endoscopy Unit, Royal London Hospital
How does Psychological Stress Exacerbate Ulcerative Colitis? Roles of mucosa-associated bacteria, mast cells and catecholamines
£85,000 (2 years)
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Dr Christine Whiting - School of Clinical Veterinary Science, University of Bristol
IL-13 promotes inflammation-induced gut fibrosis via a TNF-?-dependent mechanism
£67,106 (1 year)
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Dr Jeremy Sanderson - School of Biomedical and Health Sciences, Kings College London
The difficult problem of oral Crohn’s disease: a unique pathological entity in IBD?
£51,975 (1 year)
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Dr Louise Langmead - Department of Gastroenterology UCLH
Clinical trial to evaluate aloe vera gel enemas in mild to moderately active distal ulcerative colitis (UC)
£30,127 (1 year)
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Dr Jeremy Sanderson - School of Biomedical and Health Sciences, Kings College London
Optimising thiopurine metabolite monitoring to allow personalised thiopurine treatment
£9,300 (1 year)
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Research Awards for 2007 totalled: £243,508  

2006

Prof Subrata Ghosh - Imperial College London
Control of adaptive immune responses via Crohn’s disease-associated NOD2 signalling and bacterial sensing in human dentritic cells
£95,242 (2 years)
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Dr Amanda Williams - University of Bristol
Is selection pressure responsible for chronic refractory IBD? – Does initial steroid therapy ultimately lead to treatment failure by preferential selection of disease-propagating T cells?
£89,987 (2 years)
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Dr Andrew Smith - University College London
Macrophages from Crohn’s disease patients have an impaired response to inflammatory stimuli
£20,000 (1 year)
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Dr Gordon Dent - Keele University
Eosinophil/epithelium interactions in inflammatory bowel disease: a pilot study
£3,000 (1 year)
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Research Awards for 2006 totalled: £208,229  

2005

Professor Christopher Mathew - Guys, King’s & St Thomas’ School of Medicine
Genetic investigation of the role of the NF-kB pathway in susceptibility to inflammatory bowel disease
£89,946 (2 years)
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Professor John Hermon-Taylor - St George’s Hospital Medical School, London
Progress in the development of a prime/boost MVA/Ad5 vectored vaccine against Mycobacterium avium subspecies paratuberculosis (MAP) to treat MAP-infected Crohn's disease sufferers
£89,242 (2 years)
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Dr Geoffrey Warhurst - University of Manchester
A novel role for P-glycoprotein in regulating the interaction between the colonic epithelium and commensal gut bacteria: implications for the pathogenesis of inflammatory bowel disease
£67,339 (2 years)
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Dr Miles Parkes - Addenbrooke’s Hospital
Cambridge and Eastern IBD genetics: expanding the large-scale region-wide IBD DNA panel; Genome Partitioning to map the IBD2 locus; and analysis of Crohn's disease data from Sanger Institute case/control study
£25,501 (18 months)
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Dr David Qualtrough - University of Bristol, School of Medical Sciences
The Role of Fascin in IBD related cancer risk
£5,756 (1 year)
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Research Awards for 2005 totalled: £277,784  

2004

Dr Satish Keshav - Department of Medicine, Royal Free & University College Medical School, London
Tissue-specific and circulating effectors in Crohn’s disease.
£85,000 (2 years)
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Professor Gordon Dougan - Centre for Molecular Microbiology and Infection, Dept.of Biological Sciences, Imperial College London, London
Isolation and characterisation of E.coli in inflammatory bowel disease.
£77,741 (2 years)
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Professor Derek Jewell - Gastroenterology Unit University of Oxford, Nuffield Dept. of Medicine, Radcliffe Infirmary, Oxford
Identification of a susceptibility gene on chromosome 3 for Crohn’s disease.
£75,000 (2 years)
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Professor Subrata Ghosh - Gastroenterology Section, Division of Medicine, Imperial College London, Hammersmith Hospital, London
A prospective study of the intestinal expression of vanilloid receptor 1 in symptomatic Crohn’s disease patients and its relationship to inflammation and Crohn’s Disease Activity Index score.
£42,500 (2 years)
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Dr Miles Parkes - Addenbrookes NHS Trust, Cambridge
Cambridge and Eastern region IBD genetics.
£41,455 (1 year)
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Dr John Mansfield - Royal Victoria Infirmary, Newcastle-upon-Tyne
Histological Correlation with Genetic Variation in Crohn’s Disease
£38,000 (1 year - Funded by the Margaret Sim Legacy)
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Research Awards for 2004 totalled: £359,696  

2003

Dr Barry Campbell - Gastroenterology Research Group, University Clinical Department of Medicine, Liverpool
Investigation of IL-8 release by mucosally-adherent E.coli and Bacteroides species relevant to pathogenesis of inflammatory bowel disease.
£76,790 (2 years)
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Dr Satish Keshav - Dept of Medicine, Royal Free and University College, London NW3 2PF
New targets in IBD: Crohn’s Disease, the NOD2 gene and Paneth cells.
£74,723 (2 years)
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Dr Jeremy Sanderson - Gastroenterology Department, St Thomas’s Hospital, London
Predictive Pharmacogenomics of Thiopurine Bowel Disease.
£36,812 (1 year)
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Dr Mark Pritchard - Department of Medicine, Liverpool University, Liverpool
Investigation of the importance of the gastrin family of peptides and gastrin/CCKB receptor in inflammatory bowel disease.
£29,887 (1 year)
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Dr Jeff Behrens - Lecturer, University of East Anglia, Norwich
Can Wireless Capsule Endoscopy be of use in assessing small bowel Crohn’s Disease ? – A pilot study assessing the possible role of colour as well as traditional computer vision methods to pathogenesis of Inflammatory Bowel Disease?
£5,995 (1 year)
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Dr Geoffrey Warhurst - Gut Barrier Group, Clinical Sciences Building, University of Manchester, Manchester
Colonic gene expression in a novel model of colitis: preliminary evaluation of the molecular mechanisms by which a primary defect is the mucosal barrier leads to IBD.
£5,920 (1 year)
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Research Awards for 2003 totalled: £230,127  

2002

Dr Peter Irving - Barts and The London School of Medicine and Dentistry
Platelet-Leucocyte Aggregation in Inflammatory Bowel Disease.
£79,809 (2 years)
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Professor Jack Satsangi - Gastrointestinal Laboratory, University of Edinburgh Dept. of Medical Sciences
Gene-environmental interactions in Inflammatory Bowel Disease: the effects of NOD-2 mutations and nicotine on NF-kB activation.
£76,775 (2 years)
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Professor Derek Jewell - Department of Gastroenterology, Oxford
Identification of the HLA susceptibility gene for colonic Crohn’s disease by targeted positional cloning and microarray expression studies.
£44,838 (1 year)
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Dr Timothy Card - School of Community Health Sciences, University Hospital, Nottingham
A very large population based study of the morbidity and mortality related to Inflammatory Bowel Diseases.
£28,542 (1 year)
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Miss Miranda Lomer - Gastrointestinal Research Laboratory, The Rayne Institute, St Thomas’ Hospital, London
Assessment of large pore (particulate) permeability: A pilot study.
£5,992 (2 months)
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Dr Satish Keshav - Dept of Medicine, Royal Free & University College Medical School, London
Chimeraplast-mediated gene therapy for Crohn’s Disease.
£5,800 (9 months)
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Research Awards for 2002 totalled: £241,756  

2001

Dr S Pender - Southampton General Hospital
Functional polymorphism in the regulatory region of matrix metalloproteinase genes in Inflammatory Bowel Diseases.
£74,202 (2 years)
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Dr J Cummings - University of Dundee
The toxicity of reduced sulphur compounds in the human large intestine: A novel approach to management of Ulcerative Colitis by dietary intervention.
£69,971 (conditional after 1 year)
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Dr H Burnett - Hope Hospital, Manchester
Magnetic Resonance Imaging of the terminal ileum using the TrueFISP sequence (True Fast Imaging with Steady Precession-2 weighted gradient echo), findings compared to small bowel enema (SBE).
£10,800 (9 months)
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Dr N Cook - Central Science Laboratory, York
Development of a NASBA-based method for detection of viable Mycobacterium paratuberculosis.
£6,000 (1 year)
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Dr S Keshav - Royal Free Hospital
Phosphoinositide-3-kinase ¡ expression in colorectal carcinoma associated with Inflammatory Bowel Disease.
£5,947 (1 year)
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Dr T Trebble - Southampton General Hospital
n-3 PUFA supplementation in paediatric Crohn’s Disease: effects on disease activity and growth.
£5,521 (6 months)
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Research Awards for 2001 totalled: £172,441  

2000

Dr D Rampton - Royal London Hospital
Adverse effects of oral iron therapy in IBD prevalence, mechanism and avoidance.
£74,655 (2 years)
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Dr S Bloom - Middlesex Hospital, London
Molecular analysis of colonic mucosal microflora associated with inflammatory bowel disease.
£35,527 (1 year)
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Dr S Middleton - Addenbrooke’s Hospital, Cambridge
Detection of mini chromosome maintenance proteins in stool samples and rectal lavage specimens. An alternative to surveillance colonoscopy in ulcerative colitis?
£35,500 (1 year)
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Dr D Robertson - Royal United Hospital, Bath
Investigating the contribution and possible interaction between NF-kB and P1-3 Kinase in the TNF- a induced signalling cascades in intestinal epithelial cells.
£6,000 (1 year)
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Mr O Ogunbiyi - Royal Free Hospital, London
Investigation of the relationship between inflammatory bowel disease and familial colorectal cancer.
£5,680 (2 years)
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Dr A Hart - West Norwich Hospital
The role of diet in the aetiology of Crohn’s disease and Ulcerative colitis - a pilot study in a European prospective cohort study.
£5,451 (1 year)
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Dr M Carter - Royal Hallamshire Hospital, Sheffield
Investigation of hyperhomocysteinemia as a cause of the increased risk of thrombosis in inflammatory bowel disease.
£4,000 (1 year)
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Research Awards for 2000 totalled: £166,813  

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